Endocrine Abstracts

Background: Adrenocortical carcinomas (ACC) are rare aggressive tumors occurring at a rate of less than two per million per year. Uncommonly, there can be intravascular extension into renal veins and inferior vena cava (IVC), with resultant poorer prognosis.Clinical Case: A 26-year-old woman was referred for investigation of a two-month history of persistent left-sided abdominal pain - Computed tomography (CT) revealed a heterogeneous 12 cm left adrenal ...

Background: The Short Synacthen test (SST) is commonly used in clinical practice to evaluate adrenal function. Appropriate patient selection for SST is needed to ensure accurate interpretation of the results and to mitigate increased healthcare costs associated with unnecessary testing and inappropriate glucocorticoid (GC) steroid replacement. This study aimed to investigate the indications of inpatient SSTs over a one-year period, to determine the accuracy of testing.<p c...

IntroductionUnilateral PA can be cured with unilateral adrenalectomy. Adrenal vein sampling (AVS) is the current reference test to identify unilateral PA, but it is invasive and technically-difficult. 11C-metomidate PET-CT offers a non-invasive alternative to AVS. We compared the accuracy of AVS and PET-CT in identifying patients with unilateral surgically-curable PA.MethodsIn this prospective multi-centre cl...